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Nembutal Medical use and Euthanasia.
Pentobarbital (INN, AAN, BAN, USAN) or pentobarbitone (former AAN and BAN) is a short-acting barbiturate. Pentobarbital can occur as both a free acid and as salts of elements such as sodium and calcium. The free acid is only slightly soluble in water and ethanol.
One brand name for this drug is Nembutal, coined by John S. Lundy, who started using it in 1930, from the structural formula of the sodium salt—Na (sodium) + ethyl + methyl + butyl + al (common suffix for barbiturates).[3] Nembutal is trademarked and manufactured by the Danish pharmaceutical company Lundbeck (now produced by Akorn pharmaceuticals) and is the only injectable form of pentobarbital approved for sale in the United States.
In high doses, pentobarbital causes death by respiratory arrest. In the United States, the drug has been used for executions of convicted criminals. Lundbeck (one of many manufacturers) does not permit its sale to prisons or corrections departments to carry out the death penalty.
Medical
Typical applications for pentobarbital are sedative, hypnotic for short term, preanesthetic and control of convulsions in emergencies.
It is also used as a veterinary anesthetic agent.
Pentobarbital also has an application in reducing intracranial pressure in Reye’s syndrome, traumatic brain injury and induction of coma in cerebral ischemia patients. Pentobarbital-induced coma has been advocated in patients with acute liver failure refractory to mannitol.
Euthanasia
Pentobarbital can induce death when used in high doses. It is use for euthanasia for humans as well as animals. It is also used by itself, or in combination with complementary agents such as phenytoin, in commercial animal euthanasia injectable solutions.
In the Netherlands, the standard protocol for physician-assisted suicide is to provide 9 grams of pentobarbital sodium along with sugar syrup in a 20% ethanol solution for self-administration by the patient.
The oral dosage of pentobarbital indicated for physician-assisted death in the United States states of Oregon, Washington, Vermont, and California (as of January, 2016) is typically 10 g in liquid form. This is considerably higher than the dose for the management of status epilepticus.
After months of agony, Nembutal offered my Mom the peace she truly deserved. Her passing was serene, and we felt relief knowing she was free.
We chose quality of life over the quantity of time. Nembutal allowed my husband to leave the world on his own terms, without suffering.
Nembutal helped transform the last hours of my loved one into a time of reflection on love rather than on pain. It offered a gentler goodbye.
Nembutal ensured that my partner could maintain dignity even at the end. We cannot express our gratitude enough.
In a time of great turmoil, Nembutal was a gift of peace. I’ll forever be thankful for the choice we made.
The decision to use Nembutal was mindful and filled with compassion. It reflected our love and respect for my sister.
Thankful for the Option.
I’m thankful for the option of Nembutal during such a challenging time. It helped ease my mother’s suffering significantly.
Nembutal was an act of kindness towards my father who was suffering. His passing was a relief for him and for us
No More Pain, My sister was in constant pain due to cancer. Nembutal helped her slip away comfortably, and I will forever be grateful for that.
My father’s use of Nembutal gave our family closure. It was tough, but his peace made it a little easier to bear
Nembutal gave my loved one control over their journey at the end of life. It was a compassionate way to say farewell.
Nembutal has a relatively short to intermediate duration of action, making it suitable for various medical procedures. Other barbiturates, like phenobarbital, have a longer duration of action and are typically used for chronic conditions such as epilepsy. I am happy with my arrival.
Nembutal allowed my grandmother to leave this world gracefully, surrounded by love and comfort.
Our family made the choice together. Nembutal gave our loved one a peaceful exit, and we knew it was the right thing to do.
Goodbyes are never easy, but Nembutal simplified our experience, allowing us to focus on what truly mattered.
In a situation full of uncertainty, Nembutal brought a comforting presence to my mother’s final days.
Nembutal provided empowerment in my father’s final moments, allowing for an ending that was peaceful and loving.
Our family’s choice to use Nembutal was respected and appreciated by medical staff. It made the end-of-life journey smoother for our parents.